Sexually Dimorphic Effects of Catechol-O-Methyltransferase (COMT) Inhibition on Dopamine Metabolism in Multiple Brain Regions

The catechol-O-methyltransferase (COMT) enzyme metabolises catecholamines. COMT inhibitors are licensed for the adjunctive treatment of Parkinson's disease and are attractive therapeutic candidates for other neuropsychiatric conditions. COMT regulates dopamine levels in the prefrontal cortex (P...

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Detalles Bibliográficos
Autores principales: Laatikainen, Linda M., Sharp, Trevor, Harrison, Paul J., Tunbridge, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629045/
https://www.ncbi.nlm.nih.gov/pubmed/23613951
http://dx.doi.org/10.1371/journal.pone.0061839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629045/
https://www.ncbi.nlm.nih.gov/pubmed/23613951
http://dx.doi.org/10.1371/journal.pone.0061839

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