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Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis
Expression of the transcription factor hypoxiainducible factor 1 (HIF-1) plays a key role in cellular adaptation to hypoxia, particularly in relation to tumour angiogenesis. Expression of the HIF-1α subunit is responsive to changes in oxygen levels. Overexpression of HIF-1α has been reported to be a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629117/ https://www.ncbi.nlm.nih.gov/pubmed/23599780 http://dx.doi.org/10.3892/ol.2013.1185 |