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Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis

Expression of the transcription factor hypoxiainducible factor 1 (HIF-1) plays a key role in cellular adaptation to hypoxia, particularly in relation to tumour angiogenesis. Expression of the HIF-1α subunit is responsive to changes in oxygen levels. Overexpression of HIF-1α has been reported to be a...

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Detalles Bibliográficos
Autores principales: ZHENG, YANG, NI, YANHONG, HUANG, XIAOFENG, WANG, ZHIYONG, HAN, WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629117/
https://www.ncbi.nlm.nih.gov/pubmed/23599780
http://dx.doi.org/10.3892/ol.2013.1185