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Hypermethylation and Post-Transcriptional Regulation of DNA Methyltransferases in the Ovarian Carcinomas of the Laying Hen

DNA methyltransferases (DNMTs) are key regulators of DNA methylation and have crucial roles in carcinogenesis, embryogenesis and epigenetic modification. In general, DNMT1 has enzymatic activity affecting maintenance of DNA methylation, whereas DNMT3A and DNMT3B are involved in de novo methylation e...

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Detalles Bibliográficos
Autores principales: Lee, Jin-Young, Jeong, Wooyoung, Lim, Whasun, Lim, Chul-Hong, Bae, Seung-Min, Kim, Jinyoung, Bazer, Fuller W., Song, Gwonhwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629126/
https://www.ncbi.nlm.nih.gov/pubmed/23613894
http://dx.doi.org/10.1371/journal.pone.0061658