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HMGA2 induces epithelial-to-mesenchymal transition in human hepatocellular carcinoma cells

Epithelial-to-mesenchymal transition (EMT) is an important event during tumorigenesis. The human high-mobility group A2 (HMGA2) is a chromatin-binding protein, which contains three AT-hook domains that enable its binding to the minor groove of DNA. HMGA2 organizes protein complexes on enhancers of v...

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Detalles Bibliográficos
Autores principales: LUO, YIZHOU, LI, WENFENG, LIAO, HUI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629159/
https://www.ncbi.nlm.nih.gov/pubmed/23599793
http://dx.doi.org/10.3892/ol.2013.1193