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Enhanced De Novo Assembly of High Throughput Pyrosequencing Data Using Whole Genome Mapping
Despite major advances in next-generation sequencing, assembly of sequencing data, especially data from novel microorganisms or re-emerging pathogens, remains constrained by the lack of suitable reference sequences. De novo assembly is the best approach to achieve an accurate finished sequence, but...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629165/ https://www.ncbi.nlm.nih.gov/pubmed/23613926 http://dx.doi.org/10.1371/journal.pone.0061762 |