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Enhanced De Novo Assembly of High Throughput Pyrosequencing Data Using Whole Genome Mapping

Despite major advances in next-generation sequencing, assembly of sequencing data, especially data from novel microorganisms or re-emerging pathogens, remains constrained by the lack of suitable reference sequences. De novo assembly is the best approach to achieve an accurate finished sequence, but...

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Detalles Bibliográficos
Autores principales: Onmus-Leone, Fatma, Hang, Jun, Clifford, Robert J., Yang, Yu, Riley, Matthew C., Kuschner, Robert A., Waterman, Paige E., Lesho, Emil P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629165/
https://www.ncbi.nlm.nih.gov/pubmed/23613926
http://dx.doi.org/10.1371/journal.pone.0061762