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Expression of DNA-PKcs and BRCA1 as prognostic indicators in nasopharyngeal carcinoma following intensity-modulated radiation therapy

The mechanisms of radiation-induced effects in cancer mainly involve double-strand breaks (DSBs) which are important in maintaining the stability of genes. The DNA repair genes breast cancer 1 (BRCA1) and DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are capable of maintaining genetic st...

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Detalles Bibliográficos
Autores principales: YANG, JIAO, XU, XIMING, HAO, YANRONG, CHEN, JIAXIN, LU, HEMING, QIN, JIAN, PENG, LUXING, CHEN, BIAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629188/
https://www.ncbi.nlm.nih.gov/pubmed/23599763
http://dx.doi.org/10.3892/ol.2013.1196