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Identification of a small molecule activator of SIRT1 gene expression

Increased SIRT1 expression exerts beneficial effects in transgenic animal models, ameliorating the onset and progression of aging-related disease phenotypes in various organs including the heart. The potential beneficial effects of SIRT1 have made SIRT1 a prime therapeutic target for age-related dis...

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Detalles Bibliográficos
Autores principales: Cho, Si-Young, Cho, Miook, Seo, Dae Bang, Lee, Sang Jun, Suh, Yousin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629289/
https://www.ncbi.nlm.nih.gov/pubmed/23525956