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Suppression of epileptogenesis-associated changes in response to seizures in FGF22-deficient mice

In the developing hippocampus, fibroblast growth factor (FGF) 22 promotes the formation of excitatory presynaptic terminals. Remarkably, FGF22 knockout (KO) mice show resistance to generalized seizures in adults as assessed by chemical kindling, a model that is widely used to study epileptogenesis (...

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Detalles Bibliográficos
Autores principales: Lee, Clara H., Umemori, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629311/
https://www.ncbi.nlm.nih.gov/pubmed/23616746
http://dx.doi.org/10.3389/fncel.2013.00043