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Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6C(hi) monocyte precursors

Macrophages (mφ) are essential for intestinal homeostasis and the pathology of inflammatory bowel disease (IBD), but it is unclear whether discrete mφ populations carry out these distinct functions or if resident mφ change during inflammation. We show here that most resident mφ in resting mouse colo...

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Detalles Bibliográficos
Autores principales: Bain, C C, Scott, C L, Uronen-Hansson, H, Gudjonsson, S, Jansson, O, Grip, O, Guilliams, M, Malissen, B, Agace, W W, Mowat, A McI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629381/
https://www.ncbi.nlm.nih.gov/pubmed/22990622
http://dx.doi.org/10.1038/mi.2012.89