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Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6C(hi) monocyte precursors
Macrophages (mφ) are essential for intestinal homeostasis and the pathology of inflammatory bowel disease (IBD), but it is unclear whether discrete mφ populations carry out these distinct functions or if resident mφ change during inflammation. We show here that most resident mφ in resting mouse colo...
Autores principales: | Bain, C C, Scott, C L, Uronen-Hansson, H, Gudjonsson, S, Jansson, O, Grip, O, Guilliams, M, Malissen, B, Agace, W W, Mowat, A McI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629381/ https://www.ncbi.nlm.nih.gov/pubmed/22990622 http://dx.doi.org/10.1038/mi.2012.89 |
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