Antibody targeting of CD24 efficiently retards growth and influences cytokine milieu in experimental carcinomas

BACKGROUND: The targeting of cancer stem cells by monoclonal antibodies offers new options for therapy. CD24 is a glycosylphosphatidylinositol-anchored membrane protein with a small protein core and a high level of glycosylation. It is overexpressed in many human carcinomas and is correlated with po...

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Detalles Bibliográficos
Autores principales: Salnikov, A V, Bretz, N P, Perne, C, Hazin, J, Keller, S, Fogel, M, Herr, I, Schlange, T, Moldenhauer, G, Altevogt, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629417/
https://www.ncbi.nlm.nih.gov/pubmed/23511563
http://dx.doi.org/10.1038/bjc.2013.102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629417/
https://www.ncbi.nlm.nih.gov/pubmed/23511563
http://dx.doi.org/10.1038/bjc.2013.102

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