Transgene therapy for rat anti-Thy1.1 glomerulonephritis via mesangial cell vector with a polyethylenimine/decorin nanocomplex

Polyethylenimine (PEI), a cationic polymer, is one of the most efficient non-viral vectors for transgene therapy. Decorin (DCN), a leucine-rich proteoglycan secreted by glomerular mesangial cells (MC), is a promising anti-fibrotic agent for the treatment of glomerulonephritis. In this study, we used...

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Detalles Bibliográficos
Autores principales: Sun, Jian-Yong, Sun, Yu, Wu, Hui-Juan, Zhang, Hong-Xia, Zhao, Zhong-Hua, Chen, Qi, Zhang, Zhi-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629717/
https://www.ncbi.nlm.nih.gov/pubmed/22876812
http://dx.doi.org/10.1186/1556-276X-7-451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629717/
https://www.ncbi.nlm.nih.gov/pubmed/22876812
http://dx.doi.org/10.1186/1556-276X-7-451

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