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Low prefrontal PSA-NCAM confers risk for alcoholism-related behavior

Factors underlying vulnerability to alcoholism are largely unknown. We identified an innate endophenotype in rodents that predicted individual risk for alcohol-related behaviors that was associated with decreased expression of the neuroplasticity-related cell-adhesion molecule PSA-NCAM. Depletion of...

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Detalles Bibliográficos
Autores principales: Barker, Jacqueline M., Torregrossa, Mary M., Taylor, Jane R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629946/
https://www.ncbi.nlm.nih.gov/pubmed/22922785
http://dx.doi.org/10.1038/nn.3194