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Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue

BACKGROUND: The potential nanocarrier polyamidoamine (PAMAM) generation 5 (G5-NH(2)) dendrimer has been shown to evoke lasting neuronal depolarization and cell death in a concentration-dependent manner. In this study we explored the early progression of G5-NH(2) action in brain tissue on neuronal an...

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Detalles Bibliográficos
Autores principales: Nyitrai, Gabriella, Héja, László, Jablonkai, István, Pál, Ildikó, Visy, Júlia, Kardos, Julianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630003/
https://www.ncbi.nlm.nih.gov/pubmed/23556550
http://dx.doi.org/10.1186/1477-3155-11-9