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Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue
BACKGROUND: The potential nanocarrier polyamidoamine (PAMAM) generation 5 (G5-NH(2)) dendrimer has been shown to evoke lasting neuronal depolarization and cell death in a concentration-dependent manner. In this study we explored the early progression of G5-NH(2) action in brain tissue on neuronal an...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630003/ https://www.ncbi.nlm.nih.gov/pubmed/23556550 http://dx.doi.org/10.1186/1477-3155-11-9 |