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No relevant modulation of TRPV1-mediated trigeminal pain by intranasal carbon dioxide in healthy humans

BACKGROUND: Nasal insufflation of CO(2) has been shown to exert antinociceptive respectively antihyperalgesic effects in animal pain models using topical capsaicin with activation of TRPV1-receptor positive nociceptive neurons. Clinical benefit from CO(2) inhalation in patients with craniofacial pai...

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Detalles Bibliográficos
Autores principales: Jürgens, Tim P, Reetz, Romy, May, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630066/
https://www.ncbi.nlm.nih.gov/pubmed/23574808
http://dx.doi.org/10.1186/1129-2377-14-33