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No relevant modulation of TRPV1-mediated trigeminal pain by intranasal carbon dioxide in healthy humans
BACKGROUND: Nasal insufflation of CO(2) has been shown to exert antinociceptive respectively antihyperalgesic effects in animal pain models using topical capsaicin with activation of TRPV1-receptor positive nociceptive neurons. Clinical benefit from CO(2) inhalation in patients with craniofacial pai...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630066/ https://www.ncbi.nlm.nih.gov/pubmed/23574808 http://dx.doi.org/10.1186/1129-2377-14-33 |