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OncomiR Addiction Is Generated by a miR-155 Feedback Loop in Theileria-Transformed Leukocytes

The intracellular parasite Theileria is the only eukaryote known to transform its mammalian host cells. We investigated the host mechanisms involved in parasite-induced transformation phenotypes. Tumour progression is a multistep process, yet ‘oncogene addiction’ implies that cancer cell growth and...

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Detalles Bibliográficos
Autores principales: Marsolier, Justine, Pineau, Sandra, Medjkane, Souhila, Perichon, Martine, Yin, Qinyan, Flemington, Erik, Weitzman, Matthew D., Weitzman, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630095/
https://www.ncbi.nlm.nih.gov/pubmed/23637592
http://dx.doi.org/10.1371/journal.ppat.1003222