Cargando…
Accelerated In Vivo Proliferation of Memory Phenotype CD4(+) T-cells in Human HIV-1 Infection Irrespective of Viral Chemokine Co-receptor Tropism
CD4(+) T-cell loss is the hallmark of HIV-1 infection. CD4 counts fall more rapidly in advanced disease when CCR5-tropic viral strains tend to be replaced by X4-tropic viruses. We hypothesized: (i) that the early dominance of CCR5-tropic viruses results from faster turnover rates of CCR5(+) cells, a...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630096/ https://www.ncbi.nlm.nih.gov/pubmed/23637601 http://dx.doi.org/10.1371/journal.ppat.1003310 |