Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases

DNA methylation is an epigenetic modification that plays a crucial role in normal mammalian development, retrotransposon silencing, and cellular reprogramming. Although methylation mainly occurs on the cytosine in a CG site, non-CG methylation is prevalent in pluripotent stem cells, brain, and oocyt...

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Detalles Bibliográficos
Autores principales: Shirane, Kenjiro, Toh, Hidehiro, Kobayashi, Hisato, Miura, Fumihito, Chiba, Hatsune, Ito, Takashi, Kono, Tomohiro, Sasaki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630097/
https://www.ncbi.nlm.nih.gov/pubmed/23637617
http://dx.doi.org/10.1371/journal.pgen.1003439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630097/
https://www.ncbi.nlm.nih.gov/pubmed/23637617
http://dx.doi.org/10.1371/journal.pgen.1003439

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