Visualizing the Attack of RNase Enzymes on Dendriplexes and Naked RNA Using Atomic Force Microscopy

Cationic polymers such as poly(amidoamine), PAMAM, dendrimers have been used to electrostatically complex siRNA molecules forming dendriplexes for enhancing the cytoplasmic delivery of the encapsulated cargo. However, excess PAMAM dendrimers is typically used to protect the loaded siRNA against enzy...

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Detalles Bibliográficos
Autores principales: Abdelhady, Hosam G., Lin, Yen-Ling, Sun, Haiping, ElSayed, Mohamed E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630113/
https://www.ncbi.nlm.nih.gov/pubmed/23637890
http://dx.doi.org/10.1371/journal.pone.0061710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630113/
https://www.ncbi.nlm.nih.gov/pubmed/23637890
http://dx.doi.org/10.1371/journal.pone.0061710

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