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Biomarker Discovery by Sparse Canonical Correlation Analysis of Complex Clinical Phenotypes of Tuberculosis and Malaria

Biomarker discovery aims to find small subsets of relevant variables in ‘omics data that correlate with the clinical syndromes of interest. Despite the fact that clinical phenotypes are usually characterized by a complex set of clinical parameters, current computational approaches assume univariate...

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Detalles Bibliográficos
Autores principales: Rousu, Juho, Agranoff, Daniel D., Sodeinde, Olugbemiro, Shawe-Taylor, John, Fernandez-Reyes, Delmiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630122/
https://www.ncbi.nlm.nih.gov/pubmed/23637585
http://dx.doi.org/10.1371/journal.pcbi.1003018