Androgens Upregulate Cdc25C Protein by Inhibiting Its Proteasomal and Lysosomal Degradation Pathways

Cdc25C is a cell cycle protein of the dual specificity phosphatase family essential for activating the cdk1/Cyclin B1 complex in cells entering into mitosis. Since altered cell cycle is a hallmark of human cancers, we investigated androgen regulation of Cdc25C protein in human prostate cancer (PCa)...

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Detalles Bibliográficos
Autores principales: Chou, Yu-Wei, Zhang, Li, Muniyan, Sakthivel, Ahmad, Humera, Kumar, Satyendra, Alam, Syed Mahfuzul, Lin, Ming-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630140/
https://www.ncbi.nlm.nih.gov/pubmed/23637932
http://dx.doi.org/10.1371/journal.pone.0061934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630140/
https://www.ncbi.nlm.nih.gov/pubmed/23637932
http://dx.doi.org/10.1371/journal.pone.0061934

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