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Hepatitis C Virus Pathogen Associated Molecular Pattern (PAMP) Triggers Production of Lambda-Interferons by Human Plasmacytoid Dendritic Cells

Plasmacytoid Dendritic Cells (pDCs) represent a key immune cell in the defense against viruses. Through pattern recognition receptors (PRRs), these cells detect viral pathogen associated molecular patterns (PAMPs) and initiate an Interferon (IFN) response. pDCs produce the antiviral IFNs including t...

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Detalles Bibliográficos
Autores principales: Stone, Amy E. L., Giugliano, Silvia, Schnell, Gretja, Cheng, Linling, Leahy, Katelyn F., Golden-Mason, Lucy, Gale, Michael, Rosen, Hugo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630164/
https://www.ncbi.nlm.nih.gov/pubmed/23637605
http://dx.doi.org/10.1371/journal.ppat.1003316