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Primary Breast Cancer Tumours Contain High Amounts of IgA1 Immunoglobulin: An Immunohistochemical Analysis of a Possible Carrier of the Tumour-Associated Tn Antigen

The Tn antigen (GalNAc alpha-O-Ser/Thr) as defined by the binding of the lectin, helix pomatia agglutinin (HPA) or anti-Tn monoclonal antibodies, is known to be exposed in a majority of cancers, and it has also been shown to correlate positively with the metastatic capacity in breast carcinoma. The...

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Detalles Bibliográficos
Autores principales: Welinder, Charlotte, Baldetorp, Bo, Blixt, Ola, Grabau, Dorthe, Jansson, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630176/
https://www.ncbi.nlm.nih.gov/pubmed/23637900
http://dx.doi.org/10.1371/journal.pone.0061749