Regulator of G-Protein Signaling – 5 (RGS5) Is a Novel Repressor of Hedgehog Signaling

Hedgehog (Hh) signaling plays fundamental roles in morphogenesis, tissue repair, and human disease. Initiation of Hh signaling is controlled by the interaction of two multipass membrane proteins, patched (Ptc) and smoothened (Smo). Recent studies identify Smo as a G-protein coupled receptor (GPCR)-l...

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Detalles Bibliográficos
Autores principales: Mahoney, William M., Gunaje, Jagadambika, Daum, Guenter, Dong, Xiu Rong, Majesky, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630190/
https://www.ncbi.nlm.nih.gov/pubmed/23637832
http://dx.doi.org/10.1371/journal.pone.0061421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630190/
https://www.ncbi.nlm.nih.gov/pubmed/23637832
http://dx.doi.org/10.1371/journal.pone.0061421

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