Dimethylfumarate Suppresses Adipogenic Differentiation in 3T3-L1 Preadipocytes through Inhibition of STAT3 Activity

The excessive accumulation of adipocytes contributes to the development of obesity and obesity-related diseases. The interactions of several transcription factors, such as C/EBPβ, PPARγ, C/EBPα, Nrf2, and STAT3, are required for adipogenic differentiation. Dimethylfumarate (DMF), an immune modulator...

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Detalles Bibliográficos
Autores principales: Kang, Hyeon-Ji, Seo, Hyun-Ae, Go, Younghoon, Oh, Chang Joo, Jeoung, Nam Ho, Park, Keun-Gyu, Lee, In-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630208/
https://www.ncbi.nlm.nih.gov/pubmed/23637829
http://dx.doi.org/10.1371/journal.pone.0061411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630208/
https://www.ncbi.nlm.nih.gov/pubmed/23637829
http://dx.doi.org/10.1371/journal.pone.0061411

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