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Dimethylfumarate Suppresses Adipogenic Differentiation in 3T3-L1 Preadipocytes through Inhibition of STAT3 Activity
The excessive accumulation of adipocytes contributes to the development of obesity and obesity-related diseases. The interactions of several transcription factors, such as C/EBPβ, PPARγ, C/EBPα, Nrf2, and STAT3, are required for adipogenic differentiation. Dimethylfumarate (DMF), an immune modulator...
Autores principales: | Kang, Hyeon-Ji, Seo, Hyun-Ae, Go, Younghoon, Oh, Chang Joo, Jeoung, Nam Ho, Park, Keun-Gyu, Lee, In-Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630208/ https://www.ncbi.nlm.nih.gov/pubmed/23637829 http://dx.doi.org/10.1371/journal.pone.0061411 |
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