Effects of Somatic Mutations Are Associated with SNP in the Progression of Individual Acute Myeloid Leukemia Patient: The Two-Hit Theory Explains Inherited Predisposition to Pathogenesis

This study evaluated the effects of somatic mutations and single nucleotide polymorphisms (SNPs) on disease progression and tried to verify the two-hit theory in cancer pathogenesis. To address this issue, SNP analysis was performed using the UCSC hg19 program in 10 acute myeloid leukemia patients (...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Soyoung, Koh, Youngil, Yoon, Sung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630383/
https://www.ncbi.nlm.nih.gov/pubmed/23613680
http://dx.doi.org/10.5808/GI.2013.11.1.34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630383/
https://www.ncbi.nlm.nih.gov/pubmed/23613680
http://dx.doi.org/10.5808/GI.2013.11.1.34

Ejemplares similares