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Employing MCMC under the PPL framework to analyze sequence data in large pedigrees

The increased feasibility of whole-genome (or whole-exome) sequencing has led to renewed interest in using family data to find disease mutations. For clinical phenotypes that lend themselves to study in large families, this approach can be particularly effective, because it may be possible to obtain...

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Detalles Bibliográficos
Autores principales: Huang, Yungui, Thomas, Alun, Vieland, Veronica J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630390/
https://www.ncbi.nlm.nih.gov/pubmed/23626600
http://dx.doi.org/10.3389/fgene.2013.00059