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Population Pharmacokinetics of Intramuscular Artesunate in African Children With Severe Malaria: Implications for a Practical Dosing Regimen

Parenteral artesunate (ARS) is the drug of choice for the treatment of severe malaria. Pharmacokinetics data on intramuscular ARS are limited with respect to the main treatment group that carries the highest mortality, namely, critically ill children with severe malaria. A population pharmacokinetic...

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Detalles Bibliográficos
Autores principales: Hendriksen, ICE, Mtove, G, Kent, A, Gesase, S, Reyburn, H, Lemnge, M M, Lindegardh, N, Day, N P J, von Seidlein, L, White, N J, Dondorp, A M, Tarning, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630454/
https://www.ncbi.nlm.nih.gov/pubmed/23511715
http://dx.doi.org/10.1038/clpt.2013.26