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Population Pharmacokinetics of Intramuscular Artesunate in African Children With Severe Malaria: Implications for a Practical Dosing Regimen
Parenteral artesunate (ARS) is the drug of choice for the treatment of severe malaria. Pharmacokinetics data on intramuscular ARS are limited with respect to the main treatment group that carries the highest mortality, namely, critically ill children with severe malaria. A population pharmacokinetic...
Autores principales: | Hendriksen, ICE, Mtove, G, Kent, A, Gesase, S, Reyburn, H, Lemnge, M M, Lindegardh, N, Day, N P J, von Seidlein, L, White, N J, Dondorp, A M, Tarning, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630454/ https://www.ncbi.nlm.nih.gov/pubmed/23511715 http://dx.doi.org/10.1038/clpt.2013.26 |
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