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Granule exocytosis mediates immune surveillance of senescent cells

Senescence is a stable cell cycle arrest program that contributes to tumor suppression, organismal aging and certain wound healing responses. During liver fibrosis, for example, hepatic stellate cells initially proliferate and secrete extracellular matrix components that produce fibrosis; however, t...

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Detalles Bibliográficos
Autores principales: Sagiv, A, Biran, A, Yon, M, Simon, J, Lowe, S W, Krizhanovsky, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630483/
https://www.ncbi.nlm.nih.gov/pubmed/22751116
http://dx.doi.org/10.1038/onc.2012.206