Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions

Over two-thirds of melanomas have activating mutations in B-Raf, leading to constitutive activation of the B-Raf/MKK/ERK signaling pathway. The most prevalent mutation, B-RafV600E, promotes cancer cell behavior through mechanisms that are still incompletely defined. Here, we used a sensitive microar...

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Detalles Bibliográficos
Autores principales: Couts, K L, Anderson, E M, Gross, M M, Sullivan, K, Ahn, N G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630485/
https://www.ncbi.nlm.nih.gov/pubmed/22751131
http://dx.doi.org/10.1038/onc.2012.209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630485/
https://www.ncbi.nlm.nih.gov/pubmed/22751131
http://dx.doi.org/10.1038/onc.2012.209

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