Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase-2 as Targeted Optical Imaging Agents

[Image: see text] Cycloxygenase-2 (COX-2) is an attractive target for molecular imaging because it is an inducible enzyme that is expressed in response to inflammatory and proliferative stimuli. Recently, we reported that conjugation of indomethacin with carboxy-X-rhodamine dyes results in the forma...

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Detalles Bibliográficos
Autores principales: Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Marnett, Lawrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630741/
https://www.ncbi.nlm.nih.gov/pubmed/23488616
http://dx.doi.org/10.1021/bc300693w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630741/
https://www.ncbi.nlm.nih.gov/pubmed/23488616
http://dx.doi.org/10.1021/bc300693w

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