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Cross-species Analysis Reveals Evolving and Conserved Features of the Nuclear Factor κB (NF-κB) Proteins

NF-κB is a key regulator of immune gene expression in metazoans. It is currently unclear what changes occurred in NF-κB during animal evolution and what features remained conserved. To address this question, we compared the biochemical and functional properties of NF-κB proteins derived from human a...

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Detalles Bibliográficos
Autores principales: Ryzhakov, Grigory, Teixeira, Ana, Saliba, David, Blazek, Katrina, Muta, Tatsushi, Ragoussis, Jiannis, Udalova, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630861/
https://www.ncbi.nlm.nih.gov/pubmed/23508954
http://dx.doi.org/10.1074/jbc.M113.451153