Pluronic mixed micelles overcoming methotrexate multidrug resistance: in vitro and in vivo evaluation

A Pluronic polymeric mixed micelle delivery system was developed in this study by using Pluronic P105 and F127 block copolymers to encapsulate the antitumor compound, methotrexate (MTX). The MTX-loaded Pluronic P105/F127 mixed micelle exhibited the spherical shape with about 22 nm in diameter, high...

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Detalles Bibliográficos
Autores principales: Chen, Yanzuo, Sha, Xianyi, Zhang, Wei, Zhong, Weitong, Fan, Zhuoyang, Ren, Qiuyue, Chen, Liangcen, Fang, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630990/
https://www.ncbi.nlm.nih.gov/pubmed/23620663
http://dx.doi.org/10.2147/IJN.S42368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630990/
https://www.ncbi.nlm.nih.gov/pubmed/23620663
http://dx.doi.org/10.2147/IJN.S42368

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