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Pluronic mixed micelles overcoming methotrexate multidrug resistance: in vitro and in vivo evaluation

A Pluronic polymeric mixed micelle delivery system was developed in this study by using Pluronic P105 and F127 block copolymers to encapsulate the antitumor compound, methotrexate (MTX). The MTX-loaded Pluronic P105/F127 mixed micelle exhibited the spherical shape with about 22 nm in diameter, high...

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Detalles Bibliográficos
Autores principales:	Chen, Yanzuo, Sha, Xianyi, Zhang, Wei, Zhong, Weitong, Fan, Zhuoyang, Ren, Qiuyue, Chen, Liangcen, Fang, Xiaoling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630990/ https://www.ncbi.nlm.nih.gov/pubmed/23620663 http://dx.doi.org/10.2147/IJN.S42368

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