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Therapeutic efficiency of folated poly(ethylene glycol)-chitosan-graft-polyethylenimine-Pdcd4 complexes in H-ras12V mice with liver cancer

BACKGROUND: Chitosan and chitosan derivatives have been proposed as alternative and biocompatible cationic polymers for nonviral gene delivery. However, the low transfection efficiency and low specificity of chitosan is an aspect of this approach that must be addressed prior to any clinical applicat...

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Detalles Bibliográficos
Autores principales: Kim, You-Kyoung, Minai-Tehrani, Arash, Lee, Jae-Ho, Cho, Chong-Su, Cho, Myung-Haing, Jiang, Hu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630991/
https://www.ncbi.nlm.nih.gov/pubmed/23620665
http://dx.doi.org/10.2147/IJN.S42949