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Modulation of 11β-Hydroxysteroid Dehydrogenase as a Strategy to Reduce Vascular Inflammation

Atherosclerosis is a chronic inflammatory disease in which initial vascular damage leads to extensive macrophage and lymphocyte infiltration. Although acutely glucocorticoids suppress inflammation, chronic glucocorticoid excess worsens atherosclerosis, possibly by exacerbating systemic cardiovascula...

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Detalles Bibliográficos
Autores principales: Hadoke, Patrick W. F., Kipari, Tiina, Seckl, Jonathan R., Chapman, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Current Science Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631116/
https://www.ncbi.nlm.nih.gov/pubmed/23512604
http://dx.doi.org/10.1007/s11883-013-0320-1