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Frequency-dependent mitochondrial Ca(2+) accumulation regulates ATP synthesis in pancreatic β cells
Pancreatic β cells respond to increases in glucose concentration with enhanced metabolism, the closure of ATP-sensitive K(+) channels and electrical spiking. The latter results in oscillatory Ca(2+) influx through voltage-gated Ca(2+) channels and the activation of insulin release. The relationship...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631125/ https://www.ncbi.nlm.nih.gov/pubmed/23149488 http://dx.doi.org/10.1007/s00424-012-1177-9 |