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Germline Genetic Variation Modulates Tumor Progression and Metastasis in a Mouse Model of Neuroendocrine Prostate Carcinoma

Neuroendocrine (NE) differentiation has gained increased attention as a prostate cancer (PC) prognostic marker. The aim of this study is to determine whether host germline genetic variation influences tumor progression and metastasis in C57BL/6-Tg(TRAMP)8247Ng/J (TRAMP) mouse model of aggressive NEP...

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Detalles Bibliográficos
Autores principales: Patel, Shashank J., Molinolo, Alfredo A., Gutkind, Silvio, Crawford, Nigel P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631138/
https://www.ncbi.nlm.nih.gov/pubmed/23620793
http://dx.doi.org/10.1371/journal.pone.0061848