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Pulmonary Surfactant Preserves Viability of Alveolar Type II Cells Exposed to Polymyxin B In Vitro

BACKGROUND: Exogenous surfactant derived from animal lungs is applied for treatment of surfactant deficiency. By means of its rapid spreading properties, it could transport pharmaceutical agents to the terminal air spaces. The antimicrobial peptide Polymyxin B (PxB) is used as a topical antibiotic f...

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Detalles Bibliográficos
Autores principales: Stichtenoth, Guido, Herting, Egbert, Rüdiger, Mario, Wemhöner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631157/
https://www.ncbi.nlm.nih.gov/pubmed/23620808
http://dx.doi.org/10.1371/journal.pone.0062105