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Pharmacotherapy with Fluoxetine Restores Functional Connectivity from the Dentate Gyrus to Field CA3 in the Ts65Dn Mouse Model of Down Syndrome

Down syndrome (DS) is a high-incidence genetic pathology characterized by severe impairment of cognitive functions, including declarative memory. Impairment of hippocampus-dependent long-term memory in DS appears to be related to anatomo-functional alterations of the hippocampal trisynaptic circuit...

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Detalles Bibliográficos
Autores principales: Stagni, Fiorenza, Magistretti, Jacopo, Guidi, Sandra, Ciani, Elisabetta, Mangano, Chiara, Calzà, Laura, Bartesaghi, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631158/
https://www.ncbi.nlm.nih.gov/pubmed/23620781
http://dx.doi.org/10.1371/journal.pone.0061689