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Pharmacotherapy with Fluoxetine Restores Functional Connectivity from the Dentate Gyrus to Field CA3 in the Ts65Dn Mouse Model of Down Syndrome
Down syndrome (DS) is a high-incidence genetic pathology characterized by severe impairment of cognitive functions, including declarative memory. Impairment of hippocampus-dependent long-term memory in DS appears to be related to anatomo-functional alterations of the hippocampal trisynaptic circuit...
Autores principales: | Stagni, Fiorenza, Magistretti, Jacopo, Guidi, Sandra, Ciani, Elisabetta, Mangano, Chiara, Calzà, Laura, Bartesaghi, Renata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631158/ https://www.ncbi.nlm.nih.gov/pubmed/23620781 http://dx.doi.org/10.1371/journal.pone.0061689 |
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