PPAR Agonist-Induced Reduction of Mcp1 in Atherosclerotic Plaques of Obese, Insulin-Resistant Mice Depends on Adiponectin-Induced Irak3 Expression

Synthetic peroxisome proliferator-activated receptor (PPAR) agonists are used to treat dyslipidemia and insulin resistance. In this study, we examined molecular mechanisms that explain differential effects of a PPARα agonist (fenofibrate) and a PPARγ agonist (rosiglitazone) on macrophages during obe...

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Detalles Bibliográficos
Autores principales: Hulsmans, Maarten, Geeraert, Benjamine, Arnould, Thierry, Tsatsanis, Christos, Holvoet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631170/
https://www.ncbi.nlm.nih.gov/pubmed/23620818
http://dx.doi.org/10.1371/journal.pone.0062253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631170/
https://www.ncbi.nlm.nih.gov/pubmed/23620818
http://dx.doi.org/10.1371/journal.pone.0062253

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