Cargando…
PPAR Agonist-Induced Reduction of Mcp1 in Atherosclerotic Plaques of Obese, Insulin-Resistant Mice Depends on Adiponectin-Induced Irak3 Expression
Synthetic peroxisome proliferator-activated receptor (PPAR) agonists are used to treat dyslipidemia and insulin resistance. In this study, we examined molecular mechanisms that explain differential effects of a PPARα agonist (fenofibrate) and a PPARγ agonist (rosiglitazone) on macrophages during obe...
Autores principales: | Hulsmans, Maarten, Geeraert, Benjamine, Arnould, Thierry, Tsatsanis, Christos, Holvoet, Paul |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631170/ https://www.ncbi.nlm.nih.gov/pubmed/23620818 http://dx.doi.org/10.1371/journal.pone.0062253 |
Ejemplares similares
-
Interleukin-1 Receptor-Associated Kinase-3 Is a Key Inhibitor of Inflammation in Obesity and Metabolic Syndrome
por: Hulsmans, Maarten, et al.
Publicado: (2012) -
Low Cytochrome Oxidase 1 Links Mitochondrial Dysfunction to Atherosclerosis in Mice and Pigs
por: Holvoet, Paul, et al.
Publicado: (2017) -
Decrease of miR-146b-5p in Monocytes during Obesity Is Associated with Loss of the Anti-Inflammatory but Not Insulin Signaling Action of Adiponectin
por: Hulsmans, Maarten, et al.
Publicado: (2012) -
Adiponectin-coated nanoparticles for enhanced imaging of atherosclerotic plaques
por: Almer, Gunter, et al.
Publicado: (2011) -
CD36 Inhibitors Reduce Postprandial Hypertriglyceridemia and Protect against Diabetic Dyslipidemia and Atherosclerosis
por: Geloen, Alain, et al.
Publicado: (2012)