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Complexation of C6-Ceramide with Cholesteryl Phosphocholine – A Potent Solvent-Free Ceramide Delivery Formulation for Cells in Culture

Ceramides are potent bioactive molecules in cells. However, they are very hydrophobic molecules, and difficult to deliver efficiently to cells. We have made fluid bilayers from a short-chain D-erythro-ceramide (C6-Cer) and cholesteryl phosphocholine (CholPC), and have used this as a formulation to d...

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Detalles Bibliográficos
Autores principales: Sukumaran, Pramod, Lönnfors, Max, Långvik, Otto, Pulli, Ilari, Törnquist, Kid, Slotte, J. Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631171/
https://www.ncbi.nlm.nih.gov/pubmed/23620740
http://dx.doi.org/10.1371/journal.pone.0061290