Diethylstilboestrol Exposure Does Not Reduce Testosterone Production in Human Fetal Testis Xenografts

In rodents, in utero exposure to exogenous estrogens including diethylstilboestrol (DES) results in major suppression of steroidogenesis in fetal testes. Whether similar effects occur in the human fetal testis is equivocal. Based on the results of the rodent studies, we hypothesised that exposure of...

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Detalles Bibliográficos
Autores principales: Mitchell, Rod T., Sharpe, Richard M., Anderson, Richard A., McKinnell, Chris, Macpherson, Sheila, Smith, Lee B., Wallace, W. Hamish B., Kelnar, Christopher J. H., van den Driesche, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631175/
https://www.ncbi.nlm.nih.gov/pubmed/23620786
http://dx.doi.org/10.1371/journal.pone.0061726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631175/
https://www.ncbi.nlm.nih.gov/pubmed/23620786
http://dx.doi.org/10.1371/journal.pone.0061726

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