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Selective Activation of KCa3.1 and CRAC Channels by P(2)Y(2) Receptors Promotes Ca(2+) Signaling, Store Refilling and Migration of Rat Microglial Cells
Microglial activation involves Ca(2+) signaling, and numerous receptors can evoke elevation of intracellular Ca(2+). ATP released from damaged brain cells can activate ionotropic and metabotropic purinergic receptors, and act as a chemoattractant for microglia. Metabotropic P(2)Y receptors evoke a C...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631179/ https://www.ncbi.nlm.nih.gov/pubmed/23620825 http://dx.doi.org/10.1371/journal.pone.0062345 |