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Epigenetic Regulation of BMP2 by 1,25-dihydroxyvitamin D(3) through DNA Methylation and Histone Modification

Genetic hypercalciuric stone-forming (GHS) rats have increased intestinal Ca absorption, decreased renal tubule Ca reabsorption and low bone mass, all of which are mediated at least in part by elevated tissue levels of the vitamin D receptor (VDR). Both 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) a...

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Detalles Bibliográficos
Autores principales: Fu, Baisheng, Wang, Hongwei, Wang, Jinhua, Barouhas, Ivana, Liu, Wanqing, Shuboy, Adam, Bushinsky, David A., Zhou, Dongsheng, Favus, Murray J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631216/
https://www.ncbi.nlm.nih.gov/pubmed/23620751
http://dx.doi.org/10.1371/journal.pone.0061423