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Epigenetic Regulation of BMP2 by 1,25-dihydroxyvitamin D(3) through DNA Methylation and Histone Modification
Genetic hypercalciuric stone-forming (GHS) rats have increased intestinal Ca absorption, decreased renal tubule Ca reabsorption and low bone mass, all of which are mediated at least in part by elevated tissue levels of the vitamin D receptor (VDR). Both 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) a...
Autores principales: | Fu, Baisheng, Wang, Hongwei, Wang, Jinhua, Barouhas, Ivana, Liu, Wanqing, Shuboy, Adam, Bushinsky, David A., Zhou, Dongsheng, Favus, Murray J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631216/ https://www.ncbi.nlm.nih.gov/pubmed/23620751 http://dx.doi.org/10.1371/journal.pone.0061423 |
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